Carl F Ware Selected Research

Lymphotoxin-alpha (Lymphotoxin)

1/2020	Cutting Edge: The RNA-Binding Protein Ewing Sarcoma Is a Novel Modulator of Lymphotoxin β Receptor Signaling.
1/2020	Tumor necrosis factor overcomes immune evasion in p53-mutant medulloblastoma.
1/2018	The TNF Superfamily Molecule LIGHT Promotes the Generation of Circulating and Lung-Resident Memory CD8 T Cells following an Acute Respiratory Virus Infection.
10/2016	LTβR signalling preferentially accelerates oncogenic AKT-initiated liver tumours.
10/2016	Deletion of P2Y2 receptor reveals a role for lymphotoxin-α in fatty streak formation.
11/2013	Human CD4+CD3- innate-like T cells provide a source of TNF and lymphotoxin-αβ and are elevated in rheumatoid arthritis.
5/2013	Lymphotoxin β receptor mediates caspase-dependent tumor cell apoptosis in vitro and tumor suppression in vivo despite induction of NF-κB activation.
4/2013	Lymphotoxin network pathways shape the tumor microenvironment.
10/2012	Infection with Toxoplasma gondii alters lymphotoxin expression associated with changes in splenic architecture.
5/2011	The tumor necrosis factor family member LIGHT is a target for asthmatic airway remodeling.

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Carl F Ware Research Topics

Disease

14	Neoplasms (Cancer) 01/2022 - 04/2005
14	Infections 01/2020 - 01/2004
11	Inflammation (Inflammations) 01/2019 - 10/2002
8	Autoimmune Diseases (Autoimmune Disease) 01/2022 - 12/2004
8	Virus Diseases (Viral Diseases) 01/2018 - 01/2004
2	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2022 - 12/2020
2	Pneumonia (Pneumonitis) 01/2022 - 04/2004
2	Medulloblastoma 01/2022 - 01/2020
2	COVID-19 01/2022 - 12/2020
2	Persistent Infection 11/2020 - 08/2007
2	Vesicular Stomatitis 01/2020 - 05/2015
2	Fibrosis (Cirrhosis) 01/2020 - 05/2011
2	Carcinogenesis 10/2016 - 05/2008
2	Systemic Lupus Erythematosus (Libman-Sacks Disease) 07/2015 - 02/2015
2	Colitis 08/2014 - 11/2010
2	Rheumatoid Arthritis 11/2013 - 08/2010
1	Respiratory Insufficiency (Respiratory Failure) 01/2022
1	Cytokine Release Syndrome 12/2020
1	Postmenopausal Osteoporosis 01/2020
1	Malnutrition (Nutritional Deficiencies) 01/2020
1	Ewing Sarcoma (Sarcoma, Ewing) 01/2020
1	Type 2 Diabetes Mellitus (MODY) 01/2019
1	Diabetic Nephropathies (Diabetic Nephropathy) 01/2019
1	Lymphoma (Lymphomas) 01/2019
1	Chronic Kidney Failure (Chronic Renal Failure) 01/2019
1	Atherosclerosis 10/2016
1	Hepatitis 10/2016
1	Myocardial Infarction 10/2016
1	Thymoma (Thymic Carcinoma) 10/2016
1	Liver Neoplasms (Liver Cancer) 10/2016
1	Systemic Scleroderma (Systemic Sclerosis) 02/2015
1	Prostatic Neoplasms (Prostate Cancer) 03/2014
1	Necrosis 02/2013
1	Bacterial Infections (Bacterial Infection) 01/2013
1	Fatigue 11/2011
1	Asthma (Bronchial Asthma) 05/2011
1	Airway Remodeling 05/2011
1	Respiratory Hypersensitivity 05/2011
1	Hyperplasia 05/2011
1	Eosinophilia 05/2011
1	Tertiary Lymphoid Structures 02/2011
1	RNA Virus Infections 11/2009

Drug/Important Bio-Agent (IBA)

16	Lymphotoxin-alpha (Lymphotoxin)IBA 01/2020 - 07/2004
12	CytokinesIBA 12/2020 - 04/2004
10	Proteins (Proteins, Gene)FDA Link 01/2020 - 07/2004
8	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022 - 04/2005
5	Antiviral Agents (Antivirals)IBA 12/2020 - 01/2006
4	Interferon Type IIBA 11/2020 - 01/2006
3	LigandsIBA 01/2022 - 04/2005
3	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 01/2019 - 10/2017
3	Glycoproteins (Glycoprotein)IBA 01/2018 - 07/2004
3	Lymphotoxin beta ReceptorIBA 05/2008 - 10/2002
3	NF-kappa B (NF-kB)IBA 05/2008 - 10/2002
3	Member 14 Tumor Necrosis Factor ReceptorsIBA 07/2007 - 07/2004
2	VaccinesIBA 11/2020 - 01/2020
2	TNF Receptor-Associated Factor 3IBA 01/2020 - 11/2009
2	AntigensIBA 01/2020 - 01/2013
2	Phosphotransferases (Kinase)IBA 07/2013 - 05/2008
2	Immunoglobulin G (IgG)IBA 05/2011 - 04/2005
1	Monoclonal AntibodiesIBA 01/2022
1	Interleukin-6 (Interleukin 6)IBA 12/2020
1	CollagenIBA 01/2020
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2020
1	GlucocorticoidsIBA 01/2020
1	Protein Subunits (Protein Subunit)IBA 01/2020
1	TNF Receptor-Associated Factor 2 (TRAF2)IBA 01/2020
1	RNA-Binding Protein EWSIBA 01/2020
1	Immune Checkpoint InhibitorsIBA 01/2020
1	Neutralizing AntibodiesIBA 01/2020
1	Biomarkers (Surrogate Marker)IBA 01/2019
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2019
1	CarcinogensIBA 11/2017
1	CateninsIBA 10/2016
1	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 10/2016
1	Purinergic Receptors (Receptors, Purine)IBA 10/2016
1	NucleotidesIBA 10/2016
1	Apolipoproteins E (ApoE)IBA 10/2016
1	ApolipoproteinsIBA 10/2016
1	AutoantigensIBA 07/2015
1	B-Cell Activation Factor ReceptorIBA 05/2015
1	Antinuclear AntibodiesIBA 02/2015
1	Adenosine (Adenocard)FDA LinkGeneric 08/2014
1	AndrogensIBA 03/2014
1	Androgen Receptors (Androgen Receptor)IBA 03/2014
1	Interleukin-2 (IL2)IBA 07/2013
1	Serine (L-Serine)FDA Link 07/2013
1	CaspasesIBA 05/2013
1	Death Domain ReceptorsIBA 03/2013
1	Tumor Necrosis Factor InhibitorsIBA 01/2013
1	TNF-Related Apoptosis-Inducing LigandIBA 10/2012
1	Transforming Growth Factors (Transforming Growth Factor)IBA 05/2011
1	Interleukin-13IBA 05/2011
1	Type I Tumor Necrosis Factor ReceptorsIBA 02/2011
1	Interleukin-22 (IL-22)IBA 11/2010
1	Toll-Like Receptors (Toll-Like Receptor)IBA 11/2009

Therapy/Procedure

7	Therapeutics 01/2022 - 12/2004
3	Immunotherapy 01/2020 - 01/2006
1	Organ Transplantation 01/2020
1	Ovariectomy (Oophorectomy) 01/2020
1	Transplantation 05/2012